#255 ‒ Latest therapeutics in CVD, APOE’s role in Alzheimer’s disease and...
“One of the things that is so dangerous about this disorder is that the plaque that you get in FH is a soft plaque.” —John Kastelein The post #255 ‒ Latest therapeutics in CVD, APOE’s role in...
View Article#257 ‒ Cognitive decline, neurodegeneration, and head injuries: mitigation...
"If you're trying to maintain a basic set of cognitive functions, [it is important] to actively work on ways to increase headroom, increase absolute capacity throughout the lifespan. Because at some...
View Article#258 – AMA #48: Blood pressure—how to measure, manage, and treat high blood...
“If you care about your brain, if you care about your heart and if you care about your kidneys, you need low blood pressure. I think we can say that as confidently as we can say almost anything in...
View ArticleCan treating hearing loss improve cognitive trajectories and reduce dementia...
Age-related hearing loss is very common and has long been known to correlate strongly with cognitive decline. A just-published randomized trial sought to evaluate causality in this association. What do...
View ArticleImproving memory with transcranial neuromodulation
Research shows that noninvasive neuromodulation can improve performance in memory tasks. Is this technique simply a research tool, or is it a therapy of the future? The post Improving memory with...
View ArticleThe MIND diet on trial: can diet choices impact cognitive health?
The results were lackluster, but a closer look leaves room for other explanations The post The MIND diet on trial: can diet choices impact cognitive health? appeared first on Peter Attia.
View ArticleTargeting senescent cells for cognitive health
With the recent publication of the first clinical trial of senolytics for AD treatment, popular interest in these drugs has swelled, but is the excitement justified? The post Targeting senescent cells...
View Article#303 – A breakthrough in Alzheimer’s disease: the promising potential of...
“I have this dream that people might be able someday to benefit from klotho, this factor that naturally circulates in our body, that helps with longevity, that helps with other organ systems and...
View Article#306 – AMA #60: preventing cognitive decline, nutrition myths, lowering blood...
“Metabolic health, first and foremost, is the goal of nutrition.” —Peter Attia The post #306 – AMA #60: preventing cognitive decline, nutrition myths, lowering blood glucose, apoB, and blood pressure,...
View ArticleDoes hormone replacement therapy impact dementia risk?
A recent case-control study reports that menopausal hormone therapy is associated with increased risk of dementia, but results have little relevance for modern clinical practice The post Does hormone...
View Article#252 ‒ Latest insights on Alzheimer’s disease, cancer, exercise, nutrition,...
“My perspective has shifted as any scientist that's following data should… When new data comes out, you have to reassess things.” —Rhonda Patrick The post #252 ‒ Latest insights on Alzheimer’s disease,...
View Article#262 – AMA #49: Heart rate recovery, strength training, rucking, kidney...
“[Heart rate recovery] is one of the metrics that we should care about just as we care about VO2 max and just as we care about resting heart rate.” —Peter Attia The post #262 – AMA #49: Heart rate...
View Article#263 ‒ Concussions and head trauma: symptoms, treatment, and recovery | Micky...
“If you bring me a patient with concussion, I can pretty much tell you I can get that patient better. There are highly effective treatments with this injury.” —Micky Collins The post #263 ‒ Concussions...
View ArticleIs the frequency of menopausal symptoms an early barometer for later-in-life...
More than “bothersome”: Frequent menopausal hot flashes during sleep are associated with greater white matter hyperintensity volume The post Is the frequency of menopausal symptoms an early barometer...
View ArticleHow does APOE status impact the relationship between obesity and dementia risk?
Obesity has been reported by some to increase risk of dementia, while other studies have reported that obesity is protective against dementia. Might the effects of APOE genotype help to explain the...
View ArticleWhy is it so difficult to determine how nutrition impacts dementia risk?
When it comes to nutrition research, neither observational nor interventional studies have been able to tell the full story. A report by the Nutrition for Dementia Prevention Working Group offers ideas...
View ArticleAerobic exercise for Parkinson’s disease
The neuroprotective nature of aerobic exercise influences a variety of Parkinson’s disease symptoms, on top of its role in impacting disease risk and progression The post Aerobic exercise for...
View Article#300 – Special episode: Peter on exercise, fasting, nutrition, stem cells,...
“The probability that having a high VO2 max, high muscle mass, and high muscle strength are going to increase the length of your life and improve the quality of your life. . .is so high that to act in...
View ArticleIs Alzheimer’s disease unavoidable for individuals with a high-risk APOE...
A recent study reporting nearly 100% penetrance of the high-risk APOE-e4 variant is a lesson on the importance of unbiased sampling The post Is Alzheimer’s disease unavoidable for individuals with a...
View ArticleDon’t underestimate the importance of oral health
A meta-analysis reports that toothbrushing reduced the risk of hospital-acquired pneumonia among ICU patients, hinting at the whole-body impacts of oral hygiene The post Don’t underestimate the...
View Article#311 ‒ Longevity 101: a foundational guide to Peter’s frameworks for...
“I would say three-quarters of the benefits you can get towards a longer life, come solely from pursuing better health.” —Peter Attia The post #311 ‒ Longevity 101: a foundational guide to Peter’s...
View Article#313 – AMA #62: Protein’s impact on appetite and weight management, and uric...
"The body responds in pretty significant ways to alterations in protein availability.” —Peter Attia The post #313 – AMA #62: Protein’s impact on appetite and weight management, and uric acid’s link to...
View ArticleHigh-intensity interval training and cognitive function in older adults:...
A new study indicates that HIIT may help delay or even reverse age-related declines in memory and learning, but this exercise modality remains just one aspect of a well-balanced regimen. The post...
View Article#323 – CRISPR and the future of gene editing: scientific advances, genetic...
“One of the promises of gene editing is that it can provide a single treatment that is a cure for the disease.” —Feng Zhang The post #323 – CRISPR and the future of gene editing: scientific advances,...
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