#407 ‒ Preventing cardiovascular and Alzheimer’s disease: lowering LDL early,...
“I mean we have the knowledge to prevent heart disease now. It's applying it earlier in life that really makes the difference. That's my pitch to the 30-year-old, and there's a lot of pushback.”‒...
View ArticleBlood pressure: how to measure, manage, and treat high blood pressure (AMA...
In this “Ask Me Anything” (AMA) episode, Peter delves into the critical subject of blood pressure, which is one of the three primary causes of atherosclerosis, along with high apoB and smoking. He...
View Article#406 ‒ Migraine, cluster headache, and tension headache: symptoms, causes,...
“People should have hope, in the sense that it's very important to be as empowered as possible by keeping a log of information, by providing their clinicians or the treating physicians or providers...
View Article#404 ‒ Mental health beyond neurotransmitters: the role of hormones in...
“What I finally decided was the organizing principle was that psychiatry aims at reduction of symptoms, but not restoration of the full human experience that makes life most worthwhile.”‒ Linus Abrams...
View Article#403 ‒ Peptides: separating scientific promise from marketing hype
“Peptides as a class can be genuinely powerful, which is a reason to be more careful with them, not less. We can't normalize treating real drugs carelessly.” —Peter Attia The post #403 ‒ Peptides:...
View Article#402 ‒ NMR blood analysis: how heart disease risk, insulin resistance,...
“What is true is that NMR—a single scan—can tell you a heck of a lot more than just your cardiovascular risk, your inflammation level, your diabetes risk, your mortality risk.” —Jim Otvos The post #402...
View Article#401 ‒ How curiosity transforms medicine: extraordinary discoveries that...
“The history of medicine is full of examples where we didn't invent the underlying mechanism. We discovered it, understood it, and then engineered it into something useful.” —Peter Attia The post #401...
View ArticleLithium and Alzheimer’s disease: what to weave of this LATTICE?
A negative clinical trial leaves open questions about lithium and Alzheimer’s disease. The post Lithium and Alzheimer’s disease: what to weave of this LATTICE? appeared first on Peter Attia MD.
View Article#399 ‒ The evolution of Alzheimer’s disease and dementia care: how early...
"Early diagnosis really does make a difference now in terms of changing the trajectory of someone's cognitive health.” —Gayatri Devi The post #399 ‒ The evolution of Alzheimer’s disease and dementia...
View Article#395 – Brain lipidology: understanding APOE, cholesterol homeostasis,...
"Unfortunately, a prevalent belief out there in the real world is ‘I don't ever want to lower LDL cholesterol too much, because I'll deprive the brain and I'll injure the brain’ . . .and that is not...
View Article#392 – Genetic testing: when it’s valuable, how to choose the right test, and...
“Like every tool we have in medicine, [genetic testing] has real strengths and real limitations, and its value depends almost entirely on how thoughtfully it is used.” —Peter Attia The post #392 –...
View Article#390 ‒ AMA #84: Family health history, preventing heart disease, metabolic...
“There's a risk to doing anything, and then there's a risk to NOT doing something.” —Peter Attia The post #390 ‒ AMA #84: Family health history, preventing heart disease, metabolic health, strength...
View ArticleThere is no safe gamble with high LDL cholesterol
The pitfalls of the lipid energy model and why “lean mass hyper-responders” should still take high LDL cholesterol seriously. The post There is no safe gamble with high LDL cholesterol appeared first...
View Article#387 – AMA #83: Peptides—evaluating the science, safety, and hype in a...
“The big picture is that peptides are a legitimate, powerful class of therapeutics, but the legitimacy is confined to a relatively narrow subset of them.” —Peter Attia The post #387 – AMA #83:...
View ArticleResearch Worth Sharing, April 2026 Edition
Paternal exercise shaping offspring fitness via sperm microRNAs, mRNA COVID vaccines enhancing cancer immunotherapy, light-and-sound stimulation as a low-risk Alzheimer’s treatment, and autonomic...
View ArticleProtect the eyes, protect the brain—a potentially simple lever for dementia risk
Uncorrected cataracts may do more than blur your vision. A recent meta-analysis explores what restoring sight could mean for long-term dementia risk. The post Protect the eyes, protect the brain—a...
View Article#385 – AMA #82: Applying the tools of longevity in the real world: disease...
“Everything we're doing is simultaneously geared towards reducing the risk of chronic disease but also improving healthspan." —Peter Attia The post #385 – AMA #82: Applying the tools of longevity in...
View Article#384 – Special episode — Obicetrapib: The CETP inhibitor with cardiovascular...
"It's hard for me to mask my personal optimism around this. I love the biological plausibility of this, and I think that obicetrapib has done something that it's four predecessors has failed to do."...
View ArticleAn intriguing case of “exceptional resilience” against dementia
A 75-year-old man free of dementia despite a dominant Alzheimer’s mutation — and a possible hint for the rest of us The post An intriguing case of “exceptional resilience” against dementia appeared...
View Article#383 ‒ AMA #81: Biological aging tests, longevity training, emerging...
"If there was anything wrong with seed oils in modest quantities (again beyond the caloric effects of any oil), I'm still waiting for someone to present a convincing case for that.” —Peter Attia The...
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